EDITORIAL SECTION

Articles

The Architect of the Void: When 3D Printing Becomes the Body’s New Bone

In the quiet pressurised hum of a modern surgical suite a surgeon holds a highdefinition scan of a young patients femur On the screen a jagged dark shadow marks where an osteosarcoma has claimed its territory For decades the script for this moment has been written in cold hard steel

From Visibility to Decision Readiness: The Next Phase of Quality Maturity in Pharma

Over the past decade pharmaceutical organisations have made strong progress in both digitising and digitalising quality operations Systems such as laboratory information management systems LIMS manufacturing execution systems MES and electronic quality management systems eQMS have strengthened traceability embedded workflows and enabled real time visibility across quality processes

How Drug Patents Shape the Competitive Landscape in Pharma?

It can rightly be said that the business of pharmaceuticals is very sensitive and crucial since business is all about the manufacturing of change for the purpose of ridding the world of diseases

How Predictive Maintenance Reduces Downtime in Pharma Plants

The pharmaceutical industry is always under stress to enhance the reliability of the production adherence to the regulations and quality of the products without raising the prices and to maintain a continuous supply Machinery malfunctions are not merely a setback in this highstakes game they may compromise batch integrity postpone life and death treatments and put pressure on the market promises

Exploring the Benefits of Sustainable Clinical Trials

The landscape of clinical trials is evolving with a growing recognition that research endeavors should extend beyond scientific excellence to encompass broader societal environmental and economic considerations

How Mass Spectrometers Are Transforming the Study of Metabolomics

The mechanism of metabolomics can be described as a relatively young science which is rather popular in modern science and investigates metabolites which are the small molecules that take part in the metabolic processes inside the living organism This discipline therefore has great potential as a tool in proactively unraveling a diverse range of biological occurrences disease processes or even tre...

Techno Trends

Merck’s Calderasib Receives FDA Breakthrough Therapy Designation for Lung Cancer

Merck has secured a significant regulatory milestone for its investigational cancer therapy calderasib MK after the US Food and Drug Administration FDA granted the treatment Breakthrough Therapy designation

Projects

SCHOTT Pharma Invests $60M to Expand Glass Vial Production in Pennsylvania

SCHOTT Pharma has completed a major expansion of its manufacturing facility in Lebanon Pennsylvania with an investment exceeding USD million Supported largely by BARDA the project increases domestic production

Research Insights

Predicting unknown binding sites for transition-metal-based compounds in proteins

Transitionmetalbased compounds are promising therapeutic agents particularly in cancer treatment However predicting the binding sites of such compounds remains a major challenge In this work we investigate the applicabilit

whitepaper

Placing the Right Bets: Defining Tailored Investment Strategies for Pharma Launch

Pharmaceutical launches have become significantly harder to execute successfully As IQVIAs new white paper highlights median six month cumulative sales for innovative launches have declined by compared with pre levels reflecting shrinking market opportunities