EDITORIAL SECTION

Articles

B2B Lead Generation Pharma: High-ROI Tactics for European Markets

The European pharmaceutical industry can be called one of the most complicated and highly regulated markets in the world In the global market where a centralized approval system under the oversight of the European Medicines Agency EMA is required to the reimbursement systems specific to each country in Germany France Italy Spain and the Nordics market entry and market growth needs the accuracy of...

Achieving Full Digital Maturity in Pharma Manufacturing: A Paperless Transformation Guide

The pharmaceutical sector is changing radically as manufacturers do not rely on the past and dataintensive processes The vision of paperless pharma manufacturing is not a dream anymore it is a strategy based on the pressure of the regulators the complexity of operations and the need to accomplish faster and with accuracy production The center of this change is the digital pharma manufacturing and...

Cell and Gene Therapy's Trillion-Dollar Reckoning Is Here

Cell and gene therapies can cure diseases once thought untreatable Yet a string of commercial collapses now suggests that curing the patient and sustaining the business are two very different challenges and the industry is confronting the gap at last

Quality by Design Is a Mindset, Not a Milestone

Every medicine is a promise about consistency The tablet dispensed in Milan next spring must behave exactly like the one tested in a trial four years earlier and like the ten million made between them

Exploring the Versatility of Using 3D Spheroid Models in Research

Cell culture technology forms the foundation of modern biological and pharmaceutical research For many years twodimensional culture systems have served as standard experimental models for studying cellular behavior disease mechanisms and therapeutic responses Although these models contribute significantly to scientific discovery they cannot fully replicate the structural and functional complexity...

Fundamentals of Pharmaceutical Formulation Development

The process of changing an active drug substance into a safe and effective drug is much more complicated than it seems at first sight The core of this undertaking is pharmaceutical formulation development a science and strategic field that unites the pursuit of striking a scientific breakthrough and patient care Even the most promising drug molecule would not confer therapeutic benefits without be...

Techno Trends

Lilly’s Olomorasib Gains FDA Breakthrough Therapy Status

Eli Lilly and Company has secured Breakthrough Therapy designation from the US Food and Drug Administration FDA for olomorasib an investigational medicine being developed for adults with advanced pancreatic cancer carrying a KRAS GC mutation

Projects

Resilience and Lilly Expand Ohio Manufacturing Facility with US$750 Million Investment

Resilience a technologydriven contract development and manufacturing organisation CDMO has expanded its strategic partnership with Eli Lilly and Company to increase domestic production

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys