EDITORIAL SECTION

Articles

AI-Native R&D: Transforming Drug Discovery Through Intelligent Automation

For four decades pharmaceutical research productivity has moved stubbornly in the wrong direction A new medicine still takes ten to fifteen years to reach patients at a capitalised cost approaching US billion

Harnessing the Potential of mRNA Technology for Precision Cancer Treatment

Recent developments in medical research have highlighted the potential of mRNA as a viable approach for addressing challenges in healthcare particularly in combating infectious diseases and cancer

The Future of Oncology Clinical Trials: Adaptive, Biomarker-Led, and AI-Enabled

Oncology now absorbs close to a third of the industrys active development pipeline and a comparable share of its research budget It also carries the worst odds in medicine A molecule entering firstinhuman cancer studies has historically had a midsingledigit probability of reaching approval against roughly double that across other therapy areas For a European chief executive allocating capital acro...

What Are the Implications of the Changing Regulatory Landscape in Europe?

In an age characterized by technological progress changing geopolitical scenarios and an increasing focus on sustainability businesses in Europe are grappling with an intricate network of regulatory shifts

Advancing Pharmacovigilance Talent for AI: Overcoming Skills and Resource Barriers

In the transforming field of pharmacovigilance PV artificial intelligence AI is reshaping how drug safety is monitored and managed As PV evolves from manual reactive workflows to sophisticated AIaugmented systems the imperative for comprehensive workforce upskilling grows stronger Organisations and professionals must adapt to new technical demands regulatory requirements and ethical challenges to...

The Evolving Role of AI in Pharmaceutical Commercial Strategy

For most of the past decade the pharmaceutical industry told its artificial intelligence story from the laboratory bench Molecule generation protein structure prediction and trial simulation captured the headlines and the capital Yet the economics of this industry have never been settled in discovery alone

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys