EDITORIAL SECTION

Articles

Biopharmaceutical Facility Design for Sustainability: A Comprehensive Overview

The design and operation of biopharmaceutical facilities play a pivotal role in shaping the environmental impact of the pharmaceutical industry In recent years there has been a growing emphasis on sustainability within this sector

Multi-Omics Integration: Accelerating Precision Drug Development

The economics of pharmaceutical RD are dominated by a single line item that never appears on a balance sheet the programmes that did not work Only about one clinical programme in ten reaches approval and the cost of the nine that do not is carried entirely by the one that does

Market Access Strategies for Pharma Products in Europe: A Comprehensive Guide

The European pharmaceutical market is dynamic and diverse presenting both opportunities and challenges for companies seeking market access This guide delves into effective strategies for navigating the complexities of market access in Europe focusing on key aspects such as reimbursement pricing and overcoming market entry challenges

Understanding Pharmacodynamics: The Science behind Drug Action Mechanisms

In the complicated world of pharmacology pharmacodynamics is also a place that is a bridge between chemistry and physiology Drugs do something somewhere and this explains how they do it In a simple way pharmacodynamics studies the action of drugs the effects of drugs in terms of their biochemical and physiological effects and how the effects are generated

EU Pharma Reform 2025 Explained: What Market Access Leaders Must Know for 2026-2029

What if your EU market exclusivity depends on launching your medicine in every member state and proving its realworld value This is no longer hypothetical The historic Pharma Reform agreement of the Council of the EU of March is the first major revision of pharmaceutical legislation in more than years It will have a significant impact on the way businesses will enter the market set their prices...

What Are the Implications of the Changing Regulatory Landscape in Europe?

In an age characterized by technological progress changing geopolitical scenarios and an increasing focus on sustainability businesses in Europe are grappling with an intricate network of regulatory shifts

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys