EDITORIAL SECTION

Articles

Pharma Patent Expirations: How European Generics are changing the Market

The industry whereby most products are pharmaceuticals is usually fueled by innovation research and last but not the least patents Patents enable drug manufacturers to sell a new drug for a certain amount of time so they can indeed recover their research and development costs However once the patents for the medicine expire any different company can legally manufacture the copy of the same drug a...

Revolutionizing Biomanufacturing: Single-use Systems at the Forefront

In the rapidly evolving field of biomanufacturing singleuse systems have emerged as a gamechanger With their ability to optimize efficiency reduce contamination risks and lower costs these systems are revolutionizing the way biopharmaceuticals are produced

What Is Pharmaceutical Logistics? Top 7 Pharmaceutical Logistics Challenges and Solutions

Pharmaceutical logistics is an important part of the health systems ecosystem and ensures that drugs and medical products that are conscious of patients safely effectively and on time In the core pharmaceutical logistics management includes planning implementation and control of movement and storage of pharmaceutical goods in the supply chain Given the sensitive nature of these products it is nece...

The Cost of Uncertainty: How Analytical Chemistry Drives Billion-Dollar Decisions in Pharma

In pharmaceutical development uncertainty is not an abstract scientific inconvenience It has a cost a timeline a regulatory consequence and ultimately a patient impact A promising medicine may have strong biological rationale compelling early data and significant commercial potential yet still face a fundamental question do we truly understand the product well enough to develop manufacture approve...

The Rise of Continuous Clinical Trials: Redefining Drug Development

The conventional clinical trial is a disposable asset A sponsor writes a protocol for a single compound activates a network of sites recruits a control group reads out and then dismantles everything it has built When the next candidate arrives often in the same disease often at the same hospitals

Considerations and Functional Elements of Closed Systems: Isolators and Single Use Systems

Advances in technology have demonstrated the feasibility of using isolators and singleuse systems SUS in routine pharmaceutical manufacturing operations particularly in aseptic processing Their implementation has significantly reduced the risk of chemical particulate and microbiological contamination

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys