EDITORIAL SECTION

Articles

The Architect of the Void: When 3D Printing Becomes the Body’s New Bone

In the quiet pressurised hum of a modern surgical suite a surgeon holds a highdefinition scan of a young patients femur On the screen a jagged dark shadow marks where an osteosarcoma has claimed its territory For decades the script for this moment has been written in cold hard steel

Advancing Pharmaceutical Manufacturing with Robotics and Automation

The pharmaceutical sector is experiencing one of the most fundamental changes ever in its history triggered by the booming growth of robotics intelligent automation and AIdriven manufacturing systems Developing new and improved drugs and with increased demands on the globe the old processes based on manual labor and fragmentation are no longer able to produce drugs as quickly precisely and in larg...

How to Optimize Batch Production in European Pharmaceutical Manufacturing?

Efficient and highquality batch production is crucial for success in the European pharmaceutical industry This short introduction explores key strategies for optimizing manufacturing processes

B2B Pharma Magazines: Sponsored Thought Leadership Strategies for Brand Authority

The pharmaceutical industry has never been short of innovation Every year brings breakthroughs in biologics advanced therapies AIdriven drug discovery manufacturing automation precision medicine and digital health

Fundamentals of Pharmaceutical Formulation Development

The process of changing an active drug substance into a safe and effective drug is much more complicated than it seems at first sight The core of this undertaking is pharmaceutical formulation development a science and strategic field that unites the pursuit of striking a scientific breakthrough and patient care Even the most promising drug molecule would not confer therapeutic benefits without be...

Considerations and Functional Elements of Closed Systems: Isolators and Single Use Systems

Advances in technology have demonstrated the feasibility of using isolators and singleuse systems SUS in routine pharmaceutical manufacturing operations particularly in aseptic processing Their implementation has significantly reduced the risk of chemical particulate and microbiological contamination

Techno Trends

Lilly’s Olomorasib Gains FDA Breakthrough Therapy Status

Eli Lilly and Company has secured Breakthrough Therapy designation from the US Food and Drug Administration FDA for olomorasib an investigational medicine being developed for adults with advanced pancreatic cancer carrying a KRAS GC mutation

Projects

Resilience and Lilly Expand Ohio Manufacturing Facility with US$750 Million Investment

Resilience a technologydriven contract development and manufacturing organisation CDMO has expanded its strategic partnership with Eli Lilly and Company to increase domestic production

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys