EDITORIAL SECTION

Articles

Sustainability in Pharma Manufacturing: A Focus on Green Practices

The pharmaceutical industry is pivotal to global healthcare but its manufacturing processes typically carry a significant environmental burden In recent years there has been an increasing recognition of the importance of sustainability in pharmaceutical manufacturing

Optimizing Pharmaceutical Viral Vector Production: Techniques and Challenges

Pharmaceutical viral vectors have emerged as powerful tools in gene therapy vaccine development and biotechnology research The ability of viral vectors to deliver genetic material into target cells

Multi-Omics Integration: Accelerating Precision Drug Development

The economics of pharmaceutical RD are dominated by a single line item that never appears on a balance sheet the programmes that did not work Only about one clinical programme in ten reaches approval and the cost of the nine that do not is carried entirely by the one that does

From Molecule to Market: Building a Regulatory-Ready Manufacturing Strategy

Every pharmaceutical executive can recite the journey from molecule to market Far fewer can say with confidence at which point in that journey their manufacturing strategy became capable of withstanding a regulatory inspection The distinction matters more than it once did Approval timelines are compressing

Beyond Manual Literature Screening: From AI Automation to Decision Preparation in Pharmacovigilance in Europe

As of August the EU AI Act is generally applicable although some obligations for highrisk AI systems apply at later dates For pharmacovigilance organisations a key consideration is to determine the role and classification of each AI system under the Act rather than assuming that AI used in PV is automatically classified as highrisk AIliteracy requirements are already applicable while provider and...

Nanosizing: An Enthralling Strategy to Improve the Systemic Availability of Poorly Soluble Drugs

To enable the effective preclinical testing efficacy and safety evaluation followed by firstinman studies formulation scientists must come up with effective strategies to achieve the desired bioavailability of these poorly soluble compounds

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys