EDITORIAL SECTION

Articles

Rethinking Make-or-Buy: Strategic Manufacturing Decisions in Pharma

Few strategic decisions in pharmaceutical operations carry as much longterm consequence as the choice of what to make and what to buy and few are revisited as rarely Network footprints agreed a decade ago partners selected during a capacity crunch technology transfers completed under launch pressure these choices harden into architecture They stop looking like decisions and start looking like the...

Assessing the Impact of Tariffs on the Pharmaceutical Industry

The pharmaceutical industry function as a vital foundation for worldwide healthcare infrastructure because they push medical advancement while supporting medication availability to patients The pharmaceutical industry deals with major operational obstacles when public authorities establish tariffs for both pharmaceutical imports and exports The implementation of tariffs affects how prices shift wh...

Spleen Cytokines Against Inflammatory Bowel Disease

Over one hundred years ago at the University of Toronto Frederick Banting Charles Best and James Collip extracted protein insulin from the pancreas that saved the lives of millions of diabetics since then It is possible that the proteins extracted from the spleen can also help people with inflammatory bowel disease IBD

Digital Twins in Pharma: What They Are and Why They Matter

In the current fastpaced life sciences industry Digital Twins Pharma innovations are transforming the industrys conceptualization design testing and delivery of therapeutic products Since intelligent connected and datadriven operations have taken the center stage in pharma companies moving towards the digital age the emergence of Digital Twin Technology in Pharmaceutical structures has been a focu...

The Growing Role of Real-World Evidence in European Drug Development

For decades the randomised controlled trial has been the gold standard of pharmaceutical evidence in Europe and it still is Yet the evidence that shapes a medicines journey from laboratory to patient is no longer confined to the controlled world of the trial protocol Electronic health records disease registries insurance claims biobanks and patientreported data are now being mobilised at continent...

Navigating European Pharma Regulations: A B2B Perspective

The pharmaceutical industry in the European region practices one of the most regulating laws in the entire world Therefore regulations encompassing these areas are of prime importance for BB companies that need to achieve market entry and maintain compliance Thus this guide is meant to decompartmentalize the array of European pharma regulations and create

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys