EDITORIAL SECTION

Articles

How AI Is Addressing Drug Development Challenges in Rare Diseases?

Healthcare struggles with persistent obstacles to treat and understand rare diseases which societies call orphan diseases While affecting a minority portion of individuals these rare diseases make therapy discovery difficult because of scarce research data and expensive evaluation costs alongside multifaceted disease pathways The rising use of artificial intelligence AI drives a transformative cha...

Pain Points and Progress: Navigating the Complexities of Life Sciences Logistics

Within recent years there has been a new facet of complexity in the supply chain pathways of the life sciences industry From rising geopolitical tensions to trade wars logistics teams now have to operate in an environment shaped by rapid change regulatory scrutiny and unpredictable policy changes influenced by politics

Adapting to the Post-Brexit Pharma Environment: Strategies for Success

The pharmaceutical industry has undergone significant changes following the United Kingdoms departure from the European Union commonly known as Brexit This historic event has introduced new challenges and opportunities for pharmaceutical

AI Governance in Pharma: Managing Trust, Transparency, and Regulatory Expectations

Most large pharmaceutical organisations no longer have an AI strategy problem They have an AI accountability problem Models now sit inside pharmacovigilance case intake deviation triage visual inspection trial feasibility medical information and commercial targeting deployed by different functions on different platforms under different assumptions about who signs

Rethinking Make-or-Buy: Strategic Manufacturing Decisions in Pharma

Few strategic decisions in pharmaceutical operations carry as much longterm consequence as the choice of what to make and what to buy and few are revisited as rarely Network footprints agreed a decade ago partners selected during a capacity crunch technology transfers completed under launch pressure these choices harden into architecture They stop looking like decisions and start looking like the...

Partnership & Collaboration: The Strategic Force Shaping the Future of Pharmaceutical Growth

The pharmaceutical industry is being reshaped by a simple but powerful reality no company however large or capable can build every capability alone The sector is operating in an environment defined

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys