EDITORIAL SECTION

Articles

Artificial Intelligence and Deep/Machine Learning(AI & D/ML) or Artificial Neural Network (ANN): Implications for pharmaceutical product development processes

Producing pharmaceutical products without untoward effects but with desired qualities is not only the very basic requirement set by regulatory authorities but also indirectly decides the success of the pharma industry The pharmaceutical product development process is a combined and coordinated work from numerous divisions of the pharma industry which usually starts

How to Optimize Batch Production in European Pharmaceutical Manufacturing?

Efficient and highquality batch production is crucial for success in the European pharmaceutical industry This short introduction explores key strategies for optimizing manufacturing processes

Key Stages in Pharmaceutical Formulation Development: A Complete Guide

One of the most significant operations in the field of drug study is pharmaceutical formulation development to ensure that the medications are distributed to the patients without harm and in the most appropriate manner This is a science that involves the transformation of an active pharmaceutical ingredient API into a solid efficient and convenient dosage form To researchers manufacturers and regu...

Rethinking Make-or-Buy: Strategic Manufacturing Decisions in Pharma

Few strategic decisions in pharmaceutical operations carry as much longterm consequence as the choice of what to make and what to buy and few are revisited as rarely Network footprints agreed a decade ago partners selected during a capacity crunch technology transfers completed under launch pressure these choices harden into architecture They stop looking like decisions and start looking like the...

Efficiency in Bioprocessing: Unveiling Upstream and Downstream Operations

Bioprocessing plays a crucial role in the pharmaceutical biotechnology and healthcare industries ensuring the efficient production of biologics vaccines and other biobased products

Gene Therapy: Breakthrough Treatments for Rare Diseases

The idea of gene therapy is radically changing the sphere of medicine with the possibilities to cure the patients with the rare hereditary diseases These diseases which are usually brought about by the alteration of the sequence

Techno Trends

Lilly’s Olomorasib Gains FDA Breakthrough Therapy Status

Eli Lilly and Company has secured Breakthrough Therapy designation from the US Food and Drug Administration FDA for olomorasib an investigational medicine being developed for adults with advanced pancreatic cancer carrying a KRAS GC mutation

Projects

Resilience and Lilly Expand Ohio Manufacturing Facility with US$750 Million Investment

Resilience a technologydriven contract development and manufacturing organisation CDMO has expanded its strategic partnership with Eli Lilly and Company to increase domestic production

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys